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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FHIT
All Species:
14.24
Human Site:
S112
Identified Species:
28.48
UniProt:
P49789
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49789
NP_002003.1
147
16858
S112
G
D
F
H
R
N
D
S
I
Y
E
E
L
Q
K
Chimpanzee
Pan troglodytes
XP_001156390
66
7556
S31
G
D
F
H
R
N
D
S
I
Y
E
E
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001094642
149
17140
Y114
F
H
R
N
D
S
I
Y
E
K
L
Q
K
H
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O89106
150
17216
Y114
F
P
R
N
D
N
I
Y
D
E
L
Q
K
H
D
Rat
Rattus norvegicus
Q9JIX3
150
17329
Y114
F
R
R
N
D
N
I
Y
D
E
L
Q
K
H
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505882
135
15318
Y97
F
S
R
N
D
S
I
Y
D
E
L
Q
K
H
D
Chicken
Gallus gallus
XP_414409
148
16862
D111
G
D
F
S
R
N
D
D
V
Y
K
E
L
Q
D
Frog
Xenopus laevis
NP_001088719
148
16886
Q112
G
D
F
K
R
N
D
Q
I
Y
E
E
L
Q
D
Zebra Danio
Brachydanio rerio
NP_957034
150
17218
S113
G
D
F
E
K
N
D
S
I
Y
D
E
L
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002326061
209
23713
E174
E
I
Y
D
A
I
D
E
K
E
K
E
L
K
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_200632
180
20382
E144
E
I
Y
D
A
L
D
E
K
E
K
E
L
K
Q
Baker's Yeast
Sacchar. cerevisiae
P49775
206
23523
Y137
W
Q
G
R
R
D
E
Y
L
G
V
G
G
R
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.2
94.6
N.A.
N.A.
89.3
86.6
N.A.
70
79
76.3
76
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
44.2
95.3
N.A.
N.A.
92.6
92
N.A.
76.8
87.1
84.4
83.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
N.A.
N.A.
6.6
6.6
N.A.
0
66.6
80
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
N.A.
N.A.
20
20
N.A.
20
80
80
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
39.2
N.A.
N.A.
43.8
31
N.A.
Protein Similarity:
53.5
N.A.
N.A.
58.8
46.6
N.A.
P-Site Identity:
20
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
46.6
N.A.
N.A.
46.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
42
0
17
34
9
59
9
25
0
9
0
0
0
50
% D
% Glu:
17
0
0
9
0
0
9
17
9
42
25
59
0
0
0
% E
% Phe:
34
0
42
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
42
0
9
0
0
0
0
0
0
9
0
9
9
0
0
% G
% His:
0
9
0
17
0
0
0
0
0
0
0
0
0
34
0
% H
% Ile:
0
17
0
0
0
9
34
0
34
0
0
0
0
0
0
% I
% Lys:
0
0
0
9
9
0
0
0
17
9
25
0
34
17
25
% K
% Leu:
0
0
0
0
0
9
0
0
9
0
34
0
59
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
34
0
59
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
9
0
0
0
34
0
42
25
% Q
% Arg:
0
9
34
9
42
0
0
0
0
0
0
0
0
9
0
% R
% Ser:
0
9
0
9
0
17
0
25
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
0
0
42
0
42
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _